For this episode of BioScience Talks, we're joined by Mary Hagedorn of the Smithsonian's National Zoo and Conservation Biology Institute for a discussion about biorepositories, and specifically, a plan to place a biorepository on the Moon. Described in a recent article in BioScience, such a repository would take advantage of the Moon's naturally cold temperatures to provide safe long-term storage for cryopreserved animal tissues.