In this episode of The Mutation Station, we explore the fascinating world of hypermobility and Marfan syndrome. Hypermobility, commonly known as being double-jointed, allows individuals to extend their joints beyond the typical range of motion, while Marfan syndrome is a genetic disorder affecting connective tissue. We dive into the medical characteristics of Marfan syndrome, including cardiovascular complications, joint flexibility, and the tall, slender build typical of those with the condition. The episode also examines historical figures, such as Abraham Lincoln, who may have had Marfan syndrome, and the portrayal of this disorder in art, including El Greco’s elongated figures. We also explore cultural perceptions, myths, and legends that may have been inspired by traits of hypermobility. With references to literature, art, and famous individuals, this episode highlights the impact of genetic mutations on society and history. Tune in to discover the hidden connections between genetics, culture, and creativity.