Dr. Charlotte Hacker discusses the complex genetics behind why dogs get cancer. Despite common beliefs, larger animals like elephants and blue whales rarely get cancer due to high levels of tumor suppressor genes like p53. Unfortunately, dogs' genetic makeup, influenced by rapid, human-directed breeding practices, makes them particularly susceptible to cancer.
Dr. Hacker explains the role of DNA, mutations, proto-oncogenes, and tumor suppressor genes in cancer development. She emphasizes variability across breeds, hereditary and spontaneous mutations, and environmental factors like UV light. Preventive measures for genetic and spontaneous mutations in dogs, common cancer-related genes in different breeds, and the promise of emerging research in fields like epigenetics are also discussed.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:
https://youtu.be/uBCRRQyaTgE
https://www.youtube.com/watch?v=Q7Wvo9IjcvA
https://www.youtube.com/watch?v=VlkWnaCYvfU
Related Links:
Genetic Mutations and Dog Cancer: An Overview (article) https://www.dogcancer.com/articles/stats-and-facts/genetic-mutations-and-dog-cancer/
Chapters:
00:00 Introduction
00:21 Meet Dr. Charlotte Hacker
01:09 Understanding Dog Genetics
03:06 DNA and Its Role in Cancer
06:48 Mutations and Their Effects
18:43 Oncogenes and Tumor Suppressors
24:14 Preventing Mutations in Dogs
25:49 Conclusion and Resources
33:55 Closing Remarks and Resources
Get to know Charlotte Hacker:
https://www.dogcancer.com/people/charlotte-hacker-ms-phd/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Meet Tara Diehl and Dr. Katie Berlin and soak in hope and love as they discuss the inspiring story of Dunbar, Tara’s 12-year-old dog diagnosed with primary undifferentiated pulmonary carcinoma. From the initial harrowing diagnosis to numerous treatments, including surgery, chemotherapy, and the promising effects of Palladia, Dunbar's story is a testament to hope, resilience, and the power of a dedicated dog mom … and dog insurance!
The discussion highlights the importance of pet insurance, holistic care approaches, and the invaluable bond between pets, their owners, and veterinary teams.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer
story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Links:
Dog Cancer Survival Guide - https://dogcancerbook.com/
Apocaps – https://apocaps.com/
Chapters:
00:00 Living in the Moment: Dunbar's Journey Begins
01:03 The Diagnosis: A Vet Tech's Worst Fear
03:18 Dunbar's Personality Shines Through
06:19 The Battle with Cancer: Treatment and Hope
08:52 Insurance and Financial Relief
14:04 A Comprehensive Approach: Supplements and Alternative Therapies
17:16 Dunbar's Resilience and Joy
18:09 Dog Cancer Resources and Support
18:38 The Impact of Attitude on Treatment
19:10 Dunbar's Medical Journey
23:57 Dunbar's Miraculous Recovery
25:26 Dunbar's Current Life and Activities
26:40 The Emotional Bond with Veterinary Teams
29:47 Final Thoughts and Encouragement
33:55 Closing Remarks and Resources
Get to know Dr. Katie Berlin: https://www.dogcancer.com/people/katie-berlin-dvm/
Get to know Tara Diehl: https://www.dogcancer.com/people/tara-diehl/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Doug Thamm discusses the development and use of Tanovea, a drug for treating lymphoma in dogs. He explains the drug's origins, initially researched as a human cancer therapeutic in collaboration with Gilead Sciences, and its transition to veterinary use.
Dr. Thamm provides insights into Tanovea’s application, dosage, and effectiveness compared to the CHOP protocol, as well as its potential side effects and other possible uses in different cancer types like multiple myeloma. The episode also delves into related immunotherapy research and personal reflections from Dr. Thamm, a double cancer survivor, on his career choice in veterinary oncology.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:
https://www.youtube.com/watch?v=G0iRyKshzq8
Related Links:
Our article on lymphoma: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/
Our article on Tanovea: https://www.dogcancer.com/articles/drugs/tanovea-rabacfosadine-chemotherapy/
Get the facts on dog cancer remission: https://www.dogcancer.com/articles/stats-and-facts/dog-cancer-remission/
Chapters:
00:00 Introduction
00:13 Interview with Dr. Doug Thamm
00:26 The Early Involvement with Tanovea
00:41 Challenges and Discoveries in Drug Development
02:16 Transition from Human to Veterinary Use
02:48 Clinical Trials and Dosage Experiments
06:45 FDA Approval and Practical Use
08:05 Comparing Tanovea and CHOP Protocol
15:23 Exploring Alternative Treatments: Laverdia
18:43 Off-Label Uses and Future Research
23:46 Exploring Tanovea's Effectiveness in Blood Cancers
25:14 Cost Comparison: Tanovea vs. CHOP
26:15 Side Effects of Tanovea
28:47 Pulmonary Fibrosis and Breed-Specific Risks
32:52 Personal Cancer Journeys: Dr. Doug and His Wife
38:23 Debunking Myths About Dog Cancer Treatment
42:24 The Future of Cancer Treatment: Immunotherapy
45:23 Conclusion and Resources
Get to know Dr. Doug Thamm:
https://www.dogcancer.com/people/doug-Thammm-v-m-d-diplomate-acvim-oncology/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Narda Robinson dives into the usage of cannabis for dogs with cancer, including:
Anti-inflammatory and pain control benefits
Potential anti-cancer effects
Concerns about long-term usage
The discussion also highlights the importance of product quality, potential herb-drug interactions, environmental considerations, and the legal constraints veterinarians face.
Dr. Narda Robinson shares her insights on when and how to use cannabis products effectively, including the importance of combining them with other integrative modalities for the well-being of the dog.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Links:
Our CBD article: https://www.dogcancer.com/articles/supplements/cbd-for-dogs-with-cancer/
Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/
Chapters:
00:00 Introduction
00:13 Welcome to Dog Cancer Answers
00:38 Cannabis and Cancer: Anti-Inflammatory Benefits
02:48 Environmental Impact of Cannabis Cultivation
08:04 Using Cannabis for Dogs with Cancer
10:37 CBD and Drug Interactions
16:07 Non-Pharmacological Approaches to Healing
29:02 Legal Considerations for Veterinarians
35:55 Conclusion and Final Thoughts
Get to know Dr. Narda Robinson:
https://www.dogcancer.com/people/narda-g-robinson-do-dvm-ms-faama/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Narda Robinson, a human doctor AND a veterinarian, discusses the history and medicinal applications of CBD and THC, particularly in veterinary medicine. Focusing on her pioneering work at Colorado State University, she shares insights into the challenges and benefits of researching cannabis for canine health.
Topics covered:
The endocannabinoid system
The differences between THC and CBD
Quality control issues
The broader implications of using cannabis derivatives for conditions like epilepsy and pain management in dogs.
The potential of integrating cannabinoids into veterinary practices
Common misconceptions and safety concerns
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Links:
Our CBD article: https://www.dogcancer.com/articles/supplements/cbd-for-dogs-with-cancer/
Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/
Chapters:
00:00 Introduction
00:21 Guest Introduction: Dr. Narda Robinson
00:30 The Rise of CBD in Veterinary Medicine
00:51 Early Research and Challenges
05:04 Quality Control and Safety Concerns
09:58 Understanding Cannabis and Its Components
19:41 The Endocannabinoid System
23:01 CBD vs. THC: Effects and Applications
31:52 Current Research and Future Directions
40:00 Conclusion and Final Thoughts
Get to know Dr. Narda Robinson:
https://www.dogcancer.com/people/narda-g-robinson-do-dvm-ms-faama/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
If you’re looking at using THC and/or CBD with your dog, the choices can be confusing. Is CBD from hemp the same as from marijuana? Do you want full spectrum? Is THC the same as CBD? What’s cannabis, exactly???
Licensed veterinary technician and science writer Kate Basedow joins us to go over the key terms you’ll hear when it comes to CBD. In addition to safety, she explains why a Certificates of Analysis (COA) for quality assurance in CBD products for dogs might be important … and ventures into the endocannabinoid system's role in animals.
This episode does not address the legal issues or medical benefits of the plant … but instead provides clarity so you can have an informed conversation with your veterinarian.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Links:
Our CBD article: https://www.dogcancer.com/articles/supplements/cbd-for-dogs-with-cancer/
Check out our knowledgebase of supplements! https://www.dogcancer.com/supplements/
Chapters:
00:00 Introduction
00:21 Understanding Cannabis Terminology
01:04 Legalities and Availability of CBD and THC
02:15 Basic Cannabis Terms and Definitions
03:51 Cannabinoids and Their Effects
05:42 CBD vs. THC: Safety and Effects
07:22 Marijuana vs. Hemp
10:54 Endocannabinoid System Explained
14:25 Importance of Certificate of Analysis
18:49 Conclusion and Resources
Get to know Kate Basedow:
https://www.dogcancer.com/people/kate-basedow-lvt/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Jessica Tartof explores the benefits of Chinese herbs, vitamin A, vitamin D, and various mushrooms like turkey tail and Myco-Forte. Dr. Tartof explains how testing guides her recommendations and why trusted supplement brands are essential. Tune in to learn how these supplements can help your dog fight cancer!
Key Takeaways:
Chinese Herbs: A customizable approach depending on your dog’s condition.
Vitamins: Testing is critical before using vitamin D; vitamin A is used at safe levels.
Mushrooms: Myco-Forte and turkey tail mushrooms are trusted staples in cancer care.
Always consult your veterinarian before starting any supplements!
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:
https://www.youtube.com/watch?v=9czPvOSrfoU
https://www.youtube.com/watch?v=3kYLIbs1cFE
Related Links:
Check out our knowledgebase of supplements!
https://www.dogcancer.com/supplements/
Chapters:
00:00 Introduction
00:30 - Listener Question: Supplements for Dog Cancer
00:45 - Dr. Tartoff’s Go-To Supplements: Chinese Herbs
01:15 - Synergistic Effects of Curcumin in Chinese Formulas
01:45 - Testing Vitamin D Levels Before Supplementing
02:15 - Safe Use of Vitamin A in Dogs
02:30 - The Role of Myco-Forte and Turkey Tail Mushrooms
03:00 - Adjusting Supplement Protocols Based on Testing
03:30 - Trusted Brands for Dog Cancer Supplements
04:00 - Closing Thoughts and Resources at DogCancer.com
04:15 - Disclaimer and Podcast Credits
Get to know Dr. Jessica Tartof:
https://www.dogcancer.com/people/jessica-tartof-dvm-gdipvchmcivt-cva-cvsmt/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Recorded in late 2022 and aired in 2023, Molly Jacobson speaks with Dr. Joanne Tuohy about an innovative cancer treatment for dogs: High-Intensity Focused Ultrasound (HIFU). Learn how this technology works, its potential benefits, and its current role in veterinary clinical trials. Dr. Tuohy explains how HIFU targets tumors with precision sound waves to destroy cancer cells. Bonus: it potentially relieves pain and stimulates the immune system to attack any tumor cells that are left! If you’re interested in cutting-edge treatments and clinical trials for your dog, this episode is a must-listen.
Key Topics Covered:
What is High-Intensity Focused Ultrasound (HIFU)?
How HIFU destroys tumors using sound waves.
Benefits and safety of HIFU compared to traditional treatments.
Clinical trials for dogs with osteosarcoma.
The potential for HIFU to provide pain relief and stimulate immune responses.
Future applications of HIFU in veterinary oncology.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:
https://www.youtube.com/watch?v=uAZrPM1X8ww
https://www.youtube.com/watch?v=_92w6TTXM5c
Related Links:
https://vetmed.vt.edu/people/faculty/tuohy-joanne.html
https://www.fusfoundation.org/diseases-and-conditions/soft-tissue-tumors/
https://www.dogcancer.com/articles/types-of-dog-cancer/osteosarcoma-in-dogs/
Chapters:
00:00 Introduction
02:00 What Is Ultrasound, and How Is HIFU Different?
06:00 How HIFU Destroys Tumors with Sound Waves
09:45 Safety of HIFU for Dogs and Technicians
12:30 Precision Targeting: Avoiding Damage to Healthy Tissue
18:00 Real-Time Monitoring and Engineering Behind HIFU
22:15 Potential Benefits: Pain Relief and Immune Stimulation
26:00 Clinical Trials for Osteosarcoma: What to Expect
31:45 Future Applications of HIFU for Other Cancer Types
37:00 Aftercare for Dogs Receiving HIFU
41:00 Cost and Availability of HIFU Treatments
46:00 Advice for Dog Lovers Considering Clinical Trials
50:00 Final Thoughts on the Promise of HIFU
Get to know Dr. Joanne Tuohy:
https://www.dogcancer.com/people/joanne-tuohy-dvm-phd-dacvs-small-animal/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Meet John Mcleish, a devoted dog lover who shares his journey with Lilli, his 12-year-old Cocker Spaniel diagnosed with adenocarcinoma. His heartfelt story begins with navigating her cancer treatment during the global pandemic—which presented unique challenges—from limited veterinary access to tough decisions about chemotherapy and surgery.
John opens up about:
Recognizing early signs of illness during the pandemic lockdown.
The difficulty of advocating for Lilli amidst restricted veterinary services.
His choice to forgo chemotherapy and prioritize Lilli’s quality of life.
The support and hope he found through The Dog Cancer Survival Guide and Apocaps.
How Lilli’s spirit inspired him to stay strong, despite the emotional toll.
John’s story offers valuable insights for anyone facing tough decisions about their dog’s cancer treatment.
Key Moments:
Discover how John recognized Lilli’s symptoms and took action.
Learn about the importance of trusting your vet and seeking second opinions.
Hear how adding a new puppy to the family brought joy during a tough time.
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:
https://www.youtube.com/watch?v=KqaofR4XtBU
https://www.youtube.com/watch?v=CL7qmJN8KHw
Related Links:
The Dog Cancer Survival Guide: https://www.dogcancerbook.com
Apocaps: https://apocaps.com/
This chemotherapy article covers EVERYTHING! https://www.dogcancer.com/articles/drugs/dog-chemotherapy/
Chapters:
00:00 Introduction
00:30 First Signs of Trouble: Lilli’s Diagnosis
02:00 Navigating a Pandemic and Delayed Care
05:15 The Surgery and Initial Results
07:30 The Recurrence: Making Tough Choices
10:45 Choosing Quality of Life Over Aggressive Treatment
16:00 The Role of Intuition and Advocacy in Dog Cancer
21:15 How Puppies Can Bring Joy During Hard Times
26:30 Imprinting and Legacy: Stories of Connection
28:00 John’s Best Advice for Dog Owners Facing Cancer
34:00 A Heartfelt Thanks and Final Words of Hope
Get to know John Mcleish:
https://www.dogcancer.com/people/john-mcleish/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Kristen Lester has taken a unique journey as a general practitioner offering chemotherapy to dogs. Dr. Lester shares the inspiring cancer story of her "heart dog" Sue, the challenges of cancer treatment, and why she believes GPs can play a vital role in oncology. From safety protocols to overcoming the lack of local specialists, this episode is packed with insights for dog lovers and veterinarians alike.
What You’ll Learn in This Episode:
How Dr. Lester got into oncology through her heart dog, Sue
The role general practitioners can play in cancer treatment
Safety protocols for administering chemo in a general practice
Tools and resources for GPs interested in oncology
The pros and cons of choosing a GP versus an oncologist
Your Voice Matters!
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.
Related Videos:
https://www.youtube.com/watch?v=PNbQ4mNx938
https://www.youtube.com/watch?v=V6_fWtQbxfw
Related Links:
This chemotherapy article covers EVERYTHING! https://www.dogcancer.com/articles/drugs/dog-chemotherapy/
Looking at metronomic chemo? Here’s a great read: https://www.dogcancer.com/articles/diagnosis-and-medical-procedures/metronomic-chemotherapy-for-dogs/
Chapters:
00:00 Introduction
00:30 - Dr. Lester’s Background: General Vet Meets Oncology
01:15 - The Heart Dog Who Started It All: Sue’s Story
06:45 - What is Chemotherapy in General Practice Like?
08:30 - The Role of Palladia and Modern Cancer Drugs
12:15 - General Practitioners vs. Oncologists: Pros and Cons
19:00 - Safety Protocols for Chemo in General Practice
24:30 - Special Equipment Needed for Chemotherapy
30:15 - What Dog Owners Should Know About At-Home Chemo
35:00 - Common Cancers and Chemo Protocols GPs Can Handle
38:45 - How to Start Offering Chemo as a GP
45:15 - Resources and Support for General Practitioners
48:30 - Closing Thoughts: Fighting Cancer Together
Get to know Dr. Kristen Lester:
https://www.dogcancer.com/people/kristen-marie-lester-dvm/
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices